It is the only clinic in Switzerland approved for this treatment.ĭuring the treatment, several chemotherapies completely destroy the patients’ immune system – including the subset of T cells which mistakenly attack their own nervous system. Four years ago, thanks to the high effectiveness of the treatment and the now low mortality rate, Martin’s department together with the USZ clinic were granted approval to administer the therapy. The treatment is particularly suitable for younger people with aggressive forms of the disease. “80 percent of patients remain disease-free long-term or even forever following an autologous hematopoietic stem cell transplant,” says recently retired Professor Roland Martin, study lead and last author. A study by the Department of Neuroimmunology and MS Research at the University of Zurich (UZH) and the Department of Medical Oncology and Haematology Clinic at the University Hospital Zurich (USZ) has now pinpointed why the most effective currently available therapy – a stem cell transplant – works so well. The disease leads to paralysis, pain and permanent fatigue, among other symptoms.įortunately, there have been great advances in therapies in recent decades. MS is an autoimmune disease in which the body’s own immune system attacks the myelin sheath of the nerve cells in the brain and spinal cord. Summary: 80% of patients with multiple sclerosis remain disease-free for the long term following an autologous hematopoietic stem cell transplant.Įvery day, one person in Switzerland is diagnosed with multiple sclerosis.
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